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They are referenced to provide scientific context for the ingredients and mechanisms discussed

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The study appears online in the journal Nature Communications

Interestingly, a study reported that a rapid increase in proBDNF following status epilepticus induced by pilocarpine may be in part due to decreasing its cleavage due to a decrease in tissue plasminogen activator and an increase in plasminogen activator inhibitor-1 (PAI-1), an inhibitor of extracellular and intracellular cleavage, and that proBDNF is initially enhanced in response to the acute phase of epileptogenesis (Thomas et al