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PMID: 235 PfobAMehraraBJNelsonJAWilkinsEGPusicALSidey-GibbonsC

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Modern peptide synthesis is dominated by solid-phase peptide synthesis (SPPS), which allows for the creation of a highly pure synthetic peptide, pioneered by Bruce Merrifield and refined over decades

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Cellular NAD+ levels decline with age and metabolic stress, which has prompted interest in raising them through precursors or direct administration for energy, metabolic and longevity goals [11]

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