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10.1186/s12967-024-05011-2 93 NyulasK

The tissue it is supposed to calm simply does not have enough receptors to hear the signal

Mutations in mitochondrial DNA (mtDNA), commonly detected across cancers such as renal oncocytoma, gastric adenocarcinoma, renal cell carcinoma, bladder cancer, ovarian cancer, thyroid cancer, and pancreatic cancer, 208,209,210,211,212,213,214,215 can disrupt OXPHOS, enhance ROS production, and promote tumorigenesis

For example, synthetic estrogens such as ethinylestradiol, commonly derived from contraceptives, have demonstrated the capacity to feminize male fish at concentrations below one nanogram per liter, resulting in reproductive and developmental abnormalities