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(2017) demonstrated that mouse embryonic fibroblasts (MEFs) derived from cGas / mice exhibited reduced senescence and underwent more rapid spontaneous immortalization, compared to wild-type counterparts

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In this review, we strive to lay out the multidimensional aspects of the relationship between oxidative stress and uterine fibroids, debate the underlying mechanisms that drive this relationship, and propose several clinical implications tailored to the context of this relationship