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-1(GLP-1) 45%
(5.4) Adverse Reactions/Side Effects Most common adverse reactions (5% or greater incidence) were female genital mycotic infections, nasopharyngitis, and urinary tract infections
The plasmid DNA encapsulated by LNPs demonstrated optimal characteristics for liver targeting, including particle size of approximately 100 nm, low polydispersity (approximately 0.2), neutral surface charges, and high DNA encapsulation efficiency (Supplementary Table 4) 25
Even when BMI exceeds 30 and metabolic comorbidities are documented
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