Company Market Share Analysis 7.1.1
Multiple electronic databases were systematically searched, including PubMed/MEDLINE, Embase, Cochrane Library, and Google Scholar, covering publications from January 2020 to April 2025
Animal model studies have suggested that GLP-1RAs may cause pancreatitis and exocrine dysplasia, but in the large RCTs and a meta-analysis, GLP-1RAs did not increase the risk of pancreatitis or pancreatic cancer [82,83]
Summary Clinical Presentation Symmetrical, velvety, hyperpigmented plaques on the hair-bearing surface of the vulva and groins Histologic Features Papillomatosis and hyperkeratosis but with very mild acanthosis No melanocytic proliferation and no dermal inflammation Differential Diagnosis Lichenified eczema Physiologic hyperpigmentation Takeaway Essentials Clinical Relevant Pearls Symmetrical hyperpigmentation with brown, poorly demarcated, thickened velvet-textured plaques with verrucous excrescences Pathology Interpretation Pearls Papillomatous hyperplasia without acanthosis Hypopigmentation Post-inflammatory Hypopigmentation Clinical Features Cutaneous infections (e.g., syphilis, leprosy, herpes) and many inflammatory conditions (atopic dermatitis, pityriasis lichenoides chronica (PLC), psoriasis, lichen striatus, and lichen sclerosus) can induce post-inflammatory hypopigmentation [25] (Figs
