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In head-to-head comparison during the STEP trials, semaglutide 2.4 mg weekly produced significantly greater weight reduction than liraglutide 3.0 mg daily, approximately 15% versus 7% of body weight over similar timeframes

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Statistical analysis The sample size was calculated using G*Power 3.1.9.7 for Windows to detect an effect size of 0.4 with a power of 0.8 for adults and 0.9 for larvae and an alpha of 0.05 taking into account 5 experimental groups