stopping semaglutide after 1 week What Happens When You Stop GLP-1s — And How to Prevent Weight Regain stopping semaglutide after 1 week

Landmark trials including STEP 1 and STEP 2 (published in *New England Journal of Medicine*) demonstrated superior weight loss and lower dropout rates with stepwise escalation versus fixed-dose approaches

1 Key results: Average weight loss: -14.9% of body weight (vs -2.4% with placebo) 86.4% achieved at least 5% weight loss 69.1% achieved at least 10% weight loss 50.5% achieved at least 15% weight loss Wegovy 7.2 mg: the STEP UP trial The STEP UP trial compared semaglutide 7.2 mg with the standard 2.4 mg dose in adults with obesity over 72 weeks

Egecioglu E, Engel JA, Jerlhag E

It can be enjoyed on its own or used in mixed drinks in moderation