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After culturing for 910 days, the neurons were treated with 10 M manidipine, 5 M KN-62, or 10 M H89 for 10 min, or left untreated prior to treatment with 2 mM BHBA for another 1 or 12 h

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Adipose tissue functions as an endocrine organ, regulating energy balance and influencing metabolic and cardiovascular complications through adipokine secretion

Therefore, published preclinical work reported preferential activation of the human AMY1 receptor, with substantially lower activation of AMY3 and the calcitonin receptor in the tested systems