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Taken together, preclinical and clinical studies have demonstrated that GLP-1 receptor agonists exert pleiotropic effects extending beyond glycemic control, influencing multiple organ systems including the nervous, respiratory, hepatic, renal, cardiovascular, reproductive, and immune systems (Figure 4)

This is a complementary metabolic pathway that GLP-1 drugs do not specifically target

Ozempic can slow gastric emptying, which may affect how blood-thinning medications such as warfarin or direct oral anticoagulants (DOACs) are absorbed

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response