lost weight on semaglutide but not tirzepatide Woman shares journey of loss and gain after using COMING OFF RETATRUTIDE: THE PART

Demographic covariates such as sex, age, and hepatic or renal impairment had no or a minor influence on the exposure of oral semaglutide

Once the target dose is reached, patients will likely move to a maintenance dose, which is then continued weekly to maintain weight loss and metabolic benefits

Clinical trials demonstrate that tirzepatide alone produces substantial weight loss when: Doses are appropriately titrated (starting at 2.5 mg weekly, increasing by 2.5 mg every 4 weeks as tolerated up to 15 mg) Treatment is combined with comprehensive lifestyle modification Patients receive ongoing dietary counselling and behavioural support Adequate time is allowed (typically 612 months) to assess full therapeutic effect Many patients who feel treatment is insufficient may benefit from dose optimisation or addressing adherence barriers rather than adding another medication

Quick Answer: Tirzepatide can be safely used after gallbladder removal, as cholecystectomy is not a contraindication and does not affect the medication's pharmacokinetics or therapeutic efficacy