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Excessive excitatory signaling induced by status epilepticus or genetic mutations also increase NOX activity

Trauma in childhood and adolescence is linked to a greater severity of depressive symptoms and resistance to treatment, although recent systematic investigations have shown that notwithstanding that symptomatology is higher in depressed patients with a history of trauma, offering evidence-based psychotherapy and pharmacology allows for improvement [70]

[DOI] [PubMed] [Google Scholar] 50.Masoodi M., Mahdiabadi M.A., Mokhtare M., Agah S., Kashani A.H.F., Rezadoost A.M., Sabzikarian M., Talebi A., Sahebkar A

JCF conducted the LC-MS/MS-based experiments and acquired data