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Description

The agency also identified gaps concerning characterisation, impurities, aggregates, pharmacokinetics, toxicology and immunogenicity

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PGC-1 PGC1 binds to CCAAT/enhancer binding protein (CEBPB) to enhance CPT1A transcription, resulting in activation of FAO through PGC1/CEBPB/CPT1A/FAO signaling axis, which can promote radiation resistance of nasopharyngeal carcinoma (NPC) (Du et al., 2019)

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