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The eMTD peptide (KLNFRQKLLNLISKLFCSGT), consisting of the BH3 domain and mitochondrial targeting domain of the Noxa protein, causes cell membrane damage and necrotic cell death by interacting with voltage-dependent anion channel 2 63

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The observation of metal sulphides as neutral fragments in the unimolecular decomposition of bio-organic ions is relatively rare, and only one case has been very recently reported in a study of lead-binding metallothionein [122] (see below)