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In an observational study by investigators at The University of Texas MD Anderson Cancer Center comparing outcomes of ICIs and targeted therapy with standard chemotherapy, Jones et al reported finding no significant difference in overall survival between those receiving an ICI (15.9 months) or a targeted therapy (16.9 months) and those receiving chemotherapy (17.1 months)

Pretreatment of GLP-1 in INS-1 and MIN6 cells rescued MG and AICAR-induced cell death (Fig