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This is due to the medications dual action: it mimics the GLP-1 hormone to signal fullness to the brain while simultaneously slowing down gastric emptying

Patients generally do not experience much pain during their injections because they are superficial and quick

People with obesity often perceive tastes less intensely, and they have an inherently elevated desire for sweet and energy-dense food, said Mojca Jensterle Sever, Ph.D., of the University Medical Centre in Ljubljana, Slovenia

It has been shown previously that 14% weight loss due to a very-low-energy diet (VLED) resulted in counter-regulatory changes in appetite-regulating hormones, including a significant increase in fasting levels of ghrelin and significant reductions in the fasting levels of leptin, GLP-1, peptide YY (PYY), cholecystokinin (CCK) and amylin 48