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The normally distributed continuous variables were analyzed by T -test and the skewed variables were analyzed by MannWhitney U -test

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In another study, six weeks of 1000 mg NR supplementation per day for CKD patients improved mitochondrial metabolism, yet no effects were observed in the physical endurance of skeletal muscle 315

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72 Because of this early presentation, end-stage liver disease and development of hepatocellular malignancy may occur before the age of 1 year

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