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Traditional methods such as liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS), which integrate chromatography and mass spectrometry, are currently the mainstream techniques for detecting metabolites in tumors, but they face limitations in terms of low detection efficiency for metabolites with strong polarity, isomerism, and low ionization efficiency

Skincare products, such as creams, serums, and sun protection, are highly effective treatments for skin pigmentation conditions like melasma, post-inflammatory hyperpigmentation, rosacea, and sun spots

These ebselen related compounds either by modifying the basic structure of ebselen or incorporating some structural features of the native enzyme, a number of small-molecules of selenium compounds as functional mimics of GPx are discussed