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The former enzyme converts tyrosine to dihydroxyl-phenylalanine (DOPA), which is further converted to DA via AADC catalyzation having pyridoxal phosphate as a cofactor [12]

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Mitochondrial health declines with age, and this decline is more pronounced in highly oxidative tissues such as skeletal muscles

This outcome is thought to be an effect of all medications that increase GLP-1, because of both an increase in SDF-1-alpha and capillary density due to increased hypoxia-inducible factor 1-alpha and vascular endothelial growth factor