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A 2024 Swedish study followed 3,249 MS patients for an average of 10.6 years and found that obesity was associated with: 4 43% higher risk of reaching EDSS 3 (moderate disability) 40% higher risk of reaching EDSS 4 (significant walking impairment) More rapid cognitive decline Higher MRI activity showing new brain lesions A German study of 1,066 MS patients found that obese patients reached disability milestones more quickly than those with normal weight
While the findings are promising and provide preliminary evidence of the potential benefit of semaglutide in AUD in real-world populations, Davis said, further randomized clinical trials are needed to support its use clinically for AUD. Reference: Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R