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Wrinkle reduction Yes Regeneration and healing Yes Antioxidant effects Yes Improved skin elasticity Yes Safety of use Yes Scientific data and sources Research summary Level of evidence Preliminary Number of included studies: 20 8 studies 5 studies 4 studies 1 study 1 study 1 study Final comment: Although systematic literature analyses and results from in vitro and animal model studies indicate the effectiveness of GHK-Cu in skin regeneration and wrinkle reduction, there are no direct randomized controlled trials in humans
At the time of these studies, the roles of reactive oxygen species (ROS) in cells were poorly characterised and information on subcellular compartmentation was at best fragmentary
They appear to have other benefits in the body as well, such as a positive impact on the heart, kidneys, and liver
Ethics declarations Competing interests Authors declare no competing interest
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