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Older Adults There is also evidence that the bodys ability to absorb Vitamin B12 decreases with age thus making older adults more vulnerable

A clinical trial investigated the effect of 8-week metformin treatment on aging individuals with mild cognitive impairment (MCI) or early AD, and the results revealed that metformin is associated with improved executive function, companied by improvement in learning/memory and attention [27]

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However, patients tend to tolerate these side effects because of the significant weight loss benefits they experience - something metformin does not offer