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then animals were anaesthetized and sacrificed

We noticed that the dose of testosterone as small as 0.08 mg/kg/day, which produces a small increase of the circulating hormone, could stimulate IGF-1 to reach pubertal concentrations and increase growth velocity to values comparable to the peak growth velocity (Table 1)

The large Nordic cohort had a median follow-up of approximately 2.5 years, and the Chang 2025 study followed patients for 1 year

This dual action of promoting fat breakdown while simultaneously reducing fat storage creates the net effect of adipose tissue reduction, all occurring at the peripheral tissue level without involvement of central appetite-regulating pathways in the hypothalamus