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253 GLP-1 secretion from L-cells increases substantially in response to many cytokines such as interleukin-6, and interestingly, GLP-1 levels are elevated in patients with sepsis and are correlated with the severity of illness and clinical outcomes, although it is currently unclear if the elevation of GLP-1 levels exacerbates or alleviates pathology during sepsis

[DOI] [PubMed] [Google Scholar] 21.Pettegrew JW, Klunk WE, Panchalingam K, Kanfer JN, McClure RJ