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Headaches : Dehydration can cause headaches or make existing headaches worse

( h ) Mean changes in calcium fluorescence of all cells from AP in SemaTRAP mice with Sema-responding cells (n = 124 cells, 3 slices, 3 mice) in blue and KCl only responding cells (n = 103 cells, 3 slices, 3 mice in black

Semaglutide may be ideal for patients who: Prefer an established treatment option Have specific medical histories Respond well to GLP-1 medications Tirzepatide may be considered for patients who: Need more aggressive weight loss support Have significant weight loss goals May benefit from dual-hormone activation The best way to determine the right option is through a comprehensive medical evaluation

Available as once-weekly injectable (Ozempic/Wegovy) and once-daily oral tablet (Rybelsus)