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GPX4 deficiency enhanced cellular LPO and specifically attenuated the STING DNA-sensing pathway, thereby inhibiting innate antiviral immune responses against HSV-1 and promoting HSV-1 replication in vivo (Jia et al., 2020) These suggested that GPX4 facilitated STING activation by maintaining redox homeostasis of lipids (Jia et al., 2020)

Massage the serum in for 30 seconds or so

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Data processing and presentation were conducted using BioRadCFXManager 3.0 (Bio-Rad, Hercules, CA) and flow cytometry software from ACEA Biosciences, United States