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After it's released into your system, B12 combines with another molecule called the intrinsic factor that aids its absorption into the small intestine

To help you make a better decision, consider the following factors: Your Health Condition : If you have a medical condition that affects B-12 absorption (e.g., pernicious anemia), injections are usually more effective

The standard research protocol is 300 mcg per day, subcutaneous, administered in a fasted state, typically in the morning before food or exercise

This is why Vitamin B12 therapy can be so helpful: By getting an intramuscular injection of B12, you can bypass the GI tract and allow for up to 100% absorption into the body and straight into your cells