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Vitamin C has been shown to promote the absorption of trivalent chromium and confer protective effects against hexavalent chromium-induced hepatotoxicity ( Regarding potential risks, trivalent chromium nutritional supplementsparticularly chromium picolinatehave a high safety profile within guideline-recommended doses

In fact, many skin-focused supplements combine these two ingredients in a single formula

Most of this traces back to a 2012 US National Toxicology Program (NTP) study where hairless mice coated in Retinyl Palmitate cream and exposed to UV light developed skin tumors faster

Sordi, R., Menezes-de-Lima, O., Della-Justina, A