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Cysteine provides the raw material for intracellular GSH synthesis (62)

Glutathione is found in virtually every cell of the body and supports normal protein synthesis, enzyme function, transport, and cell function

Research in chronic wound modelsincluding diabetic and pressure ulcer experimental systems that had failed standard healing protocolsdemonstrates that TB-500 administration achieves closure rates of 75-85% compared to 35-45% with standard approaches, highlighting potential for addressing impaired healing scenarios

Thus, the difficulties in treatment are related to finding the correct dose for an individual patient