These overlapping effects not only inhibit tumour initiation and early progression but also render conventional therapies more efficacious sensitizing tumour cells to chemotherapy-mediated apoptosis, protecting normal tissues against radiation-induced oxidative damage, dampening chemotherapy-associated inflammation (e.g
An immune system that is in good health is better able to tolerate oxidative stress and minimize its effects (124)
Antioxid Redox Signal 38:599618 Che X, Brydges CR, Yu Y, Price A, Joshi S, Roy A, Lee B, Barupal DK, Cheng A, Palmer DM, Levine S, Peterson DL, Vernon SD, Bateman L, Hornig M, Montoya JG, Komaroff AL, Fiehn O, Lipkin WI (2022) Evidence for peroxisomal dysfunction and dysregulation of the CDP-choline pathway in myalgic encephalomyelitis/chronic fatigue syndrome
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