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In 2011, she successfully integrated the research capabilities from San Francisco, greatly enhancing Amgen's competitive edge in the treatment of diabetes

I would imagine thats where the biggest change in coverage stems from and there may be significant data from a Medicare perspective as well

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More serious considerations the evaluating clinician will screen for include a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (GLP-1 medications carry a boxed warning for thyroid C-cell tumors based on animal studies), a history of pancreatitis, gallbladder disease, and severe gastrointestinal conditions