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543 The JAK-STAT pathway serves as a hub for cytokine signaling, and inhibitors such as tofacitinib effectively block IL-6- and IL-23-mediated immune cell activation by competitively occupying the ATP binding site of the kinase

Semaglutide and tirzepatide are contraindicated in women with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 [10]

The medication suppresses appetite, it does not build habits