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Safety: Its important to note that while AOD-9604 demonstrated excellent safety and tolerability, the clinical development program was ultimately discontinued because efficacy for weight loss did not meet regulatory approval standards

The Mechanism Behind AOD-9604 Dosage Decisions AOD-9604 stimulates lipolysis and inhibits lipogenesis through beta-3 adrenergic receptor activation in adipose tissue, operating independently of the growth hormone receptor and IGF-1 axis

This can manifest as redness, swelling, and sometimes pain

This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)