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Daniel Drucker, an endocrinologist at the University of Toronto who conducted some of the basic peptide research that helped lead to the development of GLP-1 drugs, told me

Glutathione has been referred to as the mother of all antioxidants. When we are exposed to toxins, glutathione is used up faster than it can be produced

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First, cysteine is conjoined with glutamate through the action of glutamate cysteine ligase to produce gamma-glutamylcysteine, which proceeds to link with glycine via glutathione synthase [48]