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We are also grateful to two anonymous reviewers, whose comments have greatly improved the manuscript

Separation of proteins on a non-reducing SDS-PA gel, after addition of increasing amounts of the oxidizing agent copper chloride (CuCl 2) to GSAAT resulted in the predominance of the dimeric form, while GSAAT progressively reverted to the monomeric form as the content of the reducing agent dithiothreitol (DTT) was increased

Subgroup analyses by drug type, duration of treatment, and patient characteristics similarly showed no concerning signals

Rybelsus 7 mg can be used in many patients with mild to moderate kidney impairment, but careful monitoring is required