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For example, people with specific gastrointestinal disorders might be more susceptible to the digestive side effects of the medication

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Non-Stimulant Options : Orlistat (Xenical, Alli) Setmelanotide (Imcivree) for specific genetic conditions Lifestyle Strategies That Enhance Medication Effects Nutritional Approaches : High-protein diets to preserve lean mass Fiber supplementation to enhance satiety Mindful eating practices 2

Patients with certain GLP1R variants may experience stronger appetite suppression at lower doses, suggesting earlier morning timing could prevent excessive nausea, while others may benefit from slightly higher doses timed strategically around their peak hunger windows