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The decreased expression of TF in oligodendrocytes in the SN of PD patients may decrease the ability of oligodendrocytes to sequester excess iron, ultimately resulting in an increase in oxidative stress in dopaminergic neurons

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Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously