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The Rafaelo involves inserting a fine probe into the haemorrhoid, delivering controlled heat that causes the affected blood vessels to shrink and gradually resolve typically with minimal downtime

Oxytocin , often called the "bonding hormone," promotes emotional connection and trust

Apart from these modes of action, riboflavin has also been shown to activate specific neuroactive molecules such as vitamin B 6 (which confers neuroprotection based on a role in serotonin production) 73 , homocysteine (which has a double-edged neurological role) 74 and kynurenine involved in glutamate excitotoxicity (i.e., excess of glutamate in neural synapse, resulting in death of neural cells) 75

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