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The FDA signaled escalating enforcement, and on April 30, 2026, it proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B outsourcing facility bulks list - the mechanism that governs which substances large-scale compounders may use - with a public comment period open through June 29, 2026
Another potential problem
A structured diagnostic approach, including clinical evaluation, differential diagnosis, and assessment of therapeutic response when appropriate, is essential to avoid misdiagnosis in elderly patients with cirrhosis, as the response to HE treatment may help confirm the diagnosis (Fig
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