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In patients who have severe thrombocytopenia or any coagulation disorder that would contraindicate intramuscular injections, hepatitis B immune globulin (human) should be given only if the expected benefits outweigh the risks

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"The study findings provide new information on the risk of hospitalisation for heart failure for DPP-4 inhibitors and specifically for saxagliptin relative to sitagliptin within this class," said lead investigator Alex Fu of Georgetown University Medical Center in the US