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It is important to exhaust all options before discontinuing or reducing doses of guideline-directed medications such as renin-angiotensin-aldosterone system inhibitors and mineralocorticoid receptor antagonists

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In REDEFINE 1 , a 68-week, Phase 3a, multicenter, double-blind, placebo- and active-controlled trial, 3,417 adults with overweight or obesity but without diabetes were randomized to CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg), semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo

The insulin pump allows people with diabetes to control blood sugars with technology that