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Notably, primates who were treated at an adipotide dose of 0.43mg/kg daily for four weeks [1]: Exhibited normal levels of activity without any overt clinical signs of nausea, vomiting, or food aversion Showed normal lipid profiles that did not vary throughout the study Registered higher levels of serum creatinine from adipotide doses of 0.25mg/kg Increased urine, with mild dehydration being reported at the highest adipotide dose levels Most changes in the primates serum and urine were reversed within 28 days following discontinuation of treatment [1]

doi: 10.3390/IJMS131013065 77 SinghAKYadavDSharmaNJinJO

The case for incretin therapy was once again dismissed in 1950 by Morton Grossman, one of Ivys former students