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doi: 10.1111/j.1750-3841.2007.00286.x

In addition, the clinical dosage, individual variation, insufficient sample size, improper selection of endpoint indicators and short follow-up time may all be potential factors for the failure of antiaging clinical trials

MT-IIs documented mucosal stability and receptor potency make it a useful model compound in sublingual delivery studies particularly for comparing systemic exposure achieved via mucosal routes against injectable reference data