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10.1016/j.jep.2008.03.021 223 WengL.GuoX.LiY.YangX.HanY

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Klotho knockout mice, characterized by kidney disease and aging, also exhibited an increase in association with Beclin1 to BCL2, and a knockout of the disrupted Beclin1 improved autophagy and longevity in those mice [174]

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