Keywords: Bile acid transporters, Genetic susceptibility, Inflammation, Mitochondrial dysfunction, Oxidative stress, Personalized medicine, SLCO1B1 polymorphisms Methodology This narrative review employed a structured literature search to examine the molecular mechanisms, clinical implications, and management strategies associated with atorvastatin-induced hepatotoxicity, synthesizing findings from studies published between 2000 and 2025
Available at: Last updated 8/31/2011
Available online: [DOI] [PubMed] [Google Scholar] 17.Moher D., Pham B., Jones A., Cook D.J., Jadad A.R., Moher M., Tugwell P., Klassen T.P
This finding could be explained by a competition among selenoproteins for available selenium in the form of selenocysteine required for biosynthesis of the selenoproteins and for the selenium-incorporation machinery