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Phiel, C

More common side effects within the mentioned studies revealed mild to moderate effects like pain at site of injection or headache that was transient and disappeared after 1 month [268]

In the search for UPS regulators to modulate PKA-pCREB levels in the brain, it was found that in the snail Aplysia , the ubiquitin C-terminal hydrolase (Ap-Uch, a homolog of vertebrate Uch-L1) enhances the degradation of the polyubiquitinated R subunit of PKA (Hegde et al., 1989