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Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from porcine respiratory and reproductive virus infections

In a case report by Sani et al., the use of semaglutide 1 mg weekly over 12 months in a male with PWS and diabetes resulted in an HbA1c decrease of 3.9% and weight loss of 5.2 kg (41)

Preclinical evidence further suggests that A 2A receptor antagonists can synergize with existing therapies like levodopa while potentially mitigating troublesome side effects such as dyskinesias