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These findings may have important clinical implications for the treatment of diseases in elderly humans that are linked to increased oxidative stress

patients hospitalized with COVID-19 were overweight or had obesity

A strong letter of medical necessity should include: your BMI history over at least 12 months, documentation of weight-related comorbidities (hypertension, type 2 diabetes or prediabetes, dyslipidemia, sleep apnea), prior weight-loss attempts and their outcomes, the specific clinical trial data supporting the requested medication, and a statement that the medication is medically necessary (not cosmetic)