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Moreover, administration of exendin-4 led to a reduction in 5-HT and 5-HIAA, whereas GLP-1R antagonists increased the levels of serotonin and its metabolites [56]

Electrospray ionization mass spectrometry studies have indicated that the preferred flavonoid complexation site is the hydroxyl at carbons 3 or 5 and the adjacent 4-carbonyl group [102]