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Since diagnosis, she has been treated with OHCbl, folic acid (7.5 mg per day), and betaine (up to 6 g per day)

Nuclear factor erythroid-2-related factor 2 (Nrf2) protein levels and transcriptional activity, as well as overexpression of Nrf2-dependent genes, were shown to rise following therapy

doi: 10.1586/17446651.3.6.715 208

Moreover, tumor cell-derived exosomes genetically engineered to express a pH-sensitive fusogenic GALA peptide (WEAALAEALAEALAEHLAEALAEALEALAA) efficiently delivered tumor antigens to the cytoplasm of DCs and promoted the tumor antigen presentation of DCs via the major histocompatibility complex class I molecule 38